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European drug that blocks glutamate

Battling the MSG Myth » Sharing Media Reports and Letters Related to the Issue » European drug that blocks glutamate « Previous Next »

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Ben
Posted on Thursday, July 03, 2003 - 7:55 pm:   Delete PostPrint Post   Ban Poster IP (Moderator/Admin only)

Here is an article about memantine. Think it might help us?

Charles Baron watched for eight years as his wife, Betty,
once lively and vibrant, a leader in her St. Louis
community, slipped away, lost to the ravages of Alzheimer's
disease. He tried everything to slow her decline -
prescription drugs, nutritional supplements, diet, exercise.

"We tried everything that the doctors have been kind enough
to say is not going to harm us," Mr. Baron said. But his
efforts were of little avail. At 79, Mrs. Baron was on a
steady downhill course. She still lived at home, but Mr.
Baron relied on full-time help to care for her.

Then, in early April, Mr. Baron was listening to the radio
and heard a news report about an Alzheimer's drug,
memantine. The drug blocks a brain chemical, glutamate,
which has been implicated in nerve cell death. A new study
found that it seemed to have a modest effect in alleviating
the symptoms of advanced Alzheimer's disease.

It is not a cure; it does not reverse the disease. And, for
now, it is not sold in this country. Forest Laboratories,
which has licensed it, has applied to the Food and Drug
Administration to market it and does not expect to hear
anything until fall.

But that, Mr. Baron soon learned, was not an obstacle. The
drug is sold in Europe, and the F.D.A. generally allows
patients to import unapproved drugs for their personal use
if there is no approved treatment for their condition and if
they can supply the name and address of a doctor who will
supervise the treatment. And there are plenty of Internet
companies ready to fill the demand.

When Mr. Baron telephoned Forest, the company gave him three
places to call, two in Europe and one in the United States.
He chose the one in this country, GlobalRx, persuaded his
wife's doctor to write a prescription, and sent in his
order. Soon, the drug arrived in the mail and Betty Baron
began taking it.

Over the past few months, Internet companies said, demand
for the drug has surged. GlobalRx, which has just four
full-time employees, says it had 150 memantine clients a few
months ago. Now, with about 600, it says it cannot handle
any more orders.

A British company, International Antiaging Systems, which
will ship the drug even without a doctor's order, says that
until recently it was supplying 50 patients a month. Now it
is supplying about 500, most of whom are in the United
States. The families pay for memantine out of pocket,
typically $150 to $175 a month, plus about $60 for express
delivery.

Continued at link above

COMMENT: My stepmother's father is taking this drug and it
seems to be helping him in that it has stopped the
progression of his illness. Perhaps this drug will one day
make it into the USA for general use. Till then, it is
available via mail-order from other countries.
Roy Piwovar
Posted on Friday, July 04, 2003 - 4:04 am:   Delete PostPrint Post   Ban Poster IP (Moderator/Admin only)

Ben,

Lithium orotate might do the same thing cheaper, and a diet eliminating MSG might do it for free.

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=8675405&dopt=Abstract
Jerry Story
Posted on Saturday, July 05, 2003 - 8:36 am:   Delete PostPrint Post   Ban Poster IP (Moderator/Admin only)

About glutamate blockers:

The medics make themselves look like a horse's ass. First they say the glutamate theory is "not generally accepted". Then they come up with glutamate blockers.
Anonymous
Posted on Friday, July 07, 2006 - 8:19 pm:   Delete PostPrint Post   Ban Poster IP (Moderator/Admin only)

Ein Schloss, Ein Wurst, Ein Kopf !qw

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