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MSG/ Excitotoxin Related Links

Battling the MSG Myth » Archive » MSG/ Excitotoxin Related Links « Previous Next »

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The NoMSG site is now up and runningTom Fernstrom19 11-23-00  4:49 am
Autism, ADHD, Aspergers etc & DietDeb A.7-29-01  5:59 pm
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Roy Piwovar
Posted on Thursday, November 09, 2000 - 3:00 am:   Delete PostPrint Post   Ban Poster IP (Moderator/Admin only)

Here's a new article about aspartame and memory loss:

http://my.webmd.com/content/article/1728.63559
MEMorrisNJ
Posted on Thursday, November 09, 2000 - 4:56 am:   Delete PostPrint Post   Ban Poster IP (Moderator/Admin only)

Here is another discussion group that may be of interest:

http://www.foodcanmakeyouill.co.uk

I have posted the msgmyth.com web site with its members.
Roy Piwovar
Posted on Thursday, November 16, 2000 - 6:00 pm:   Delete PostPrint Post   Ban Poster IP (Moderator/Admin only)

I went ahead and posted the above links on

http://www.NoMSG.com
Gerry Bush
Posted on Friday, November 17, 2000 - 4:06 pm:   Delete PostPrint Post   Ban Poster IP (Moderator/Admin only)

Roy, Sure wish I had copied more from the site before it crashed!
Roy Piwovar
Posted on Saturday, November 18, 2000 - 5:38 am:   Delete PostPrint Post   Ban Poster IP (Moderator/Admin only)

Gerry,

When I caught the site back up again, intact, I wanted to copy it all in case it went down again, but was at work and couldn't spare the time. When I got home, it was gone again, never to return with the files.

The lesson here is that every site has to assign someone to back things up, at the very least on a monthly basis, so that not everything is lost.

If anyone out there has files they have saved, I hope they send them in.
M-Y
Posted on Friday, November 24, 2000 - 2:07 pm:   Delete PostPrint Post   Ban Poster IP (Moderator/Admin only)

Here also is a good website.
http://www.truthinlabeling.org/produce-1.html
MEMorrisNJ
Posted on Thursday, December 07, 2000 - 6:37 am:   Delete PostPrint Post   Ban Poster IP (Moderator/Admin only)

Here are some fairly new internet sites that I found VERY interesting:

http://www.egroups.com/subscribe/STOP-Food-Chemical-Poisoning (The subscription is free.)

http://www.foodcanmakeyouill.co.uk/
MEMorrisNJ
Posted on Saturday, December 09, 2000 - 4:16 am:   Delete PostPrint Post   Ban Poster IP (Moderator/Admin only)

Try this very informative site dedicated to aspartame:

http://www.dorway.com

Try using the search feature at the dorway site to look up other topics such as MSG, milk, Dr. Blaylock, etc. Lots there!
Frank
Posted on Monday, December 11, 2000 - 1:12 pm:   Delete PostPrint Post   Ban Poster IP (Moderator/Admin only)

Take the test and see how many pesticides you brough home with your food:

http://www.foodnews.org/supermarket.html
Frank
Posted on Monday, December 11, 2000 - 1:19 pm:   Delete PostPrint Post   Ban Poster IP (Moderator/Admin only)

Wow! I have 18 pesticides in my kitchen.
It seems that while we are working to keep our bodies free of MSG, our farmers are helping us fill our bodies with new treats.
Deb A.
Posted on Monday, December 11, 2000 - 3:03 pm:   Delete PostPrint Post   Ban Poster IP (Moderator/Admin only)

Thanks, Frank!...I wish I HADN'T taken the test!
You did better than I did. I try to find as many organic products in my locality as I can. I never realized how many pesticides were on the main foods we rely on. Reading about all the food additives, alone, is enough to make a person paranoid.

MEMorris, I enjoyed visiting that site. Excellent. I read most of Dr. Blaylock's interview posted there, but I'm fighting a nasty "bug", and need to rest in bed some more before I get back to it. Been out of commission (sinus, throat infection...ugh!) for a few days and have missed reading all of your posts. Hope all of you are well and enjoying the holidays...I still have shopping to do, so this better pass soon!
Roy Piwovar
Posted on Monday, December 11, 2000 - 4:24 pm:   Delete PostPrint Post   Ban Poster IP (Moderator/Admin only)

This link says that MSG causes vasoconstriction of the blood vessels, which causes tissues to become acidic and release histamine, which leads to the familiar MSG headache:

http://www.chiroweb.com/archives/17/23/10.html

If histamine causes a wide range of allergy symptoms, then MSG should bring about all of the same ones, on top of its own.
Deb S
Posted on Monday, December 11, 2000 - 7:34 pm:   Delete PostPrint Post   Ban Poster IP (Moderator/Admin only)

Frank -- Thanks for posting that link. I had seen that before when surfing the Environmental Working Group website, but forgot just how many different pesticides (many having several ways they can harm us) are present in what we eat.

I am somewhat comforted by the many organic products I now routinely choose to buy, and this just strengthens my resolve to always buy organic when available, even when tempted by lower prices for "conventional." It's more incentive to take that trip across town to another market if necessary. I blame organophosphates (chlorpyrifos) for triggering my hyper-sensitivities to excitotoxins, fragrances, and many other substances, so avoiding pesticides is now almost an obsession.
Deb A.
Posted on Tuesday, December 12, 2000 - 9:46 am:   Delete PostPrint Post   Ban Poster IP (Moderator/Admin only)

Hi Deb S. What has led you to believe that organophosphates were responsible for triggering your other sensitivities, including MSG? This is very intriguing and a great subject for all of us to look at. I am also very sensitive to fragrances, and I react to the formaldehyde that is the finishes on fabrics. Many years ago, in the early 70's, vinyl coats were very "in", and I remember that after a short time of wearing mine, I began to notice that I would feel headachey, a little dizzy, and just "off". I quit wearing the coat, but had become more sensitive to other substances, too. We are victims of the 20th century's chemical discoveries. It frightens me to think about it.
Carol H
Posted on Tuesday, December 12, 2000 - 1:29 pm:   Delete PostPrint Post   Ban Poster IP (Moderator/Admin only)

I was reading a book on wastewater treatment (exciting reading for a civil engineer:)) Anyway, in my book it states that 10,000 new chemicals are released into the world each year. Because of this, there is no possible way we can know what the consequences are for our planet. And, there is only so much civil engineers can do to clean up the mess. To add to that, Chlorpyrifos (a.k.a. Dursban) is probably something nearly all Americans have been exposed to. The old bug sprays we used all contained it. We not only were exposed to it in what we ate, and in our water, we were encouraged to dose ourselves quite heavily in our own homes in the pursuit of killing bugs quickly with Black Flag or Raid.
Deb S
Posted on Tuesday, December 12, 2000 - 4:12 pm:   Delete PostPrint Post   Ban Poster IP (Moderator/Admin only)

Deb A. - I typed up a lengthy response and then went to find a few more links to add at the bottom, and went into a bookmarked site without opening a new window first (oops) - when I hit "Back" the message box was blank. :( Arghh! I think if I was using Internet Explorer instead of Netscape that wouldn't have happened. Oh well.

I will try again later. Meanwhile, here are a few websites I found informative:

http://www.ewg.org/pub/home/reports/ops/oppress.html
http://www.ewg.org/
http://www.chem-tox.com/
http://www.osha-slc.gov/SLTC/multiplechemicalsensitivities/index.html
http://www.ciin.org/index.htm
Deb S
Posted on Tuesday, December 12, 2000 - 8:17 pm:   Delete PostPrint Post   Ban Poster IP (Moderator/Admin only)

Well, the short answer is I accidentally came across information on the Web linking Dursban/chlorpyrifos to multiple chemical sensitivity, which I had never heard of. I also read that some people exposed to Dursban tested as having an abnormally high level of auto-antibodies, or auto-immunity.

I'll preface this with the fact that two years ago, I could eat most anything without any problems, and was in fact subsisting mostly on prepared frozen dinners, packaged lunchmeat and occasional fast-food, Equal in my coffee and diet soda.

The rental duplex I've lived in for going on 4 years is plagued with small ants, especially in the spring. In Spring 1998, at my mother's recommendation, I requested that the landlord hire Guardian Pest Control to treat my home. They did the outside and inside treatment (came back a second time to do another section of cupboards). They sprayed the foundation each month after that until Winter. The ants were back the following Spring, so I had them come again and on 4/15/99 the applicator had just finished spraying the foundation and eaves when I arrived at home to let him inside. I had planned on having the inside treated but wasn't prepared, so I talked to the guy inside for around 20 minutes about other things I could do short of spraying inside. For the past few months I was having some migraines and trouble focusing at work, which began (again) when I was put on oral contraceptives to regulate my periods. But when I took myself off the Pill, the migraines persisted and where they had been only during my period, now they were happening at other times as well. (Previous to going off the Pill in 1995, I'd had monthly migraines for about 6 years, which doctors chalked up to estrogen drop-off.)

On 4/30/99, Day 3 of another migraine I wasn't supposed to be having, the idea to search the Internet for information about Aspartame came to me. After about 5 minutes, I swore off those blue packets forever. Further searching led to information about MSG and how if you react to one, you probably react to the other. After eliminating aspartame and learning to avoid hidden sources of MSG for 4 months, my hair started falling out in large amounts (not patches, just all over). Over a couple of months, my hair went from thick to thin. I should be getting healthier, not going bald! I tried to search for causes of hair loss, but nothing seemed to fit my situation.

I saw a link to an article called "Overexposed" about pesticide exposures to children (see first link, above) and followed it. That led to other information about pesticides, especially organophosphates, linking them to multiple chemical sensitivity. This explained my newly developed sensitivities to foods that previously gave me no problems. And auto-immunity seemed a likely cause of hair loss. And I called Guardian and confirmed what I already knew: they had used two Dursban products on 4/15/99 (and no doubt throughout 1998).

Looking back, I can also link earlier periods of concentrated pesticide exposure with the appearance of other sensitivities. In the mid-'80s my apartment was treated 3 or 4 times for roaches: I suddenly could not drink as much alcohol as I had before, and suffered much worse hangovers (wondered if I was becoming allergic), I started having those diarrhea blackout episodes, and colognes I had liked before I now couldn't tolerate. In 1990 I tried everything out there to rid my cat of fleas (before Advantage came out) - shampoos, powders, sprays, collars and bombs. (Later, Dursban was taken out of pet products.) After a year or more of that, the monthly sore neck and shoulders began, which evolved into predictable two-day "migraines." I also started getting frequent sinus infections.

I'm sorry this is so long, but you asked!! :) And I have left out a lot of details.

More sites about pesticides hazards and Multiple Chemical Senstivity:

http://www.nettally.com/prusty/mcs.htm
http://www.asehaqld.org.au/chemical_sensitivity.htm
http://www.beyondpesticides.org/
http://www.nrdc.org/health/pesticides/default.asp
http://www.bandursban.org
http://www.wri.org/wri/wr-98-99/pestrisk.htm
http://www.ecomall.com/greenshopping/pirgtx2.htm
http://www.asehaqld.org.au/chemical_sensitivity.htm
Deb S
Posted on Wednesday, December 13, 2000 - 5:26 am:   Delete PostPrint Post   Ban Poster IP (Moderator/Admin only)

I should add that I am now also sensitive to lots of different fragrances, chemicals, flowers, cig. smoke, lotions, fabrics, etc., that didn't use to bother me, or only were vaguely annoying. Immediate reactions are brain fog, sinus swelling and then headache and sore neck, which go away when I get some fresh air. Someone at my office had a floral arrangement with those huge lilies one week, and my work really suffered that whole week. That same person also has this one hand lotion that the minute she puts it on I feel it. Luckily, after it dries it seems to stop bothering me. Chemical sensitivities can be to all sorts of chemicals and substances, including those in foods.

After having my MCS theory tested time and again with unexpected exposures to offending substances, I'm fairly sure that my self-diagnosis is correct. I plan to follow up with a visit to an environmental medicine physician in a month or so, when I figure out how to pay for it (not covered by my HMO).
Deb A.
Posted on Wednesday, December 13, 2000 - 12:12 pm:   Delete PostPrint Post   Ban Poster IP (Moderator/Admin only)

Deb S., thanks for again sharing such valuable information. Your theories are very plausible from what I have read so far. From what Carol has told us about the incredible amount of chemical substances we have been forced to eat, drink and breathe, it's a miracle we can function at all! I live in the apple orchard region of Washington state, and even though Dursban has been outlawed, it's been reported that the orchard owners, knowing full well in advance that it would soon be banned, stockpiled Dursban. The law as it is, allows them to continue to use the supplies the orchards have in their possession. So along with neurotoxins we have to handle in our foods, we have to contend with the neural disruptive properties of Dursban for who knows how much longer. The many acres of orchards just 2 blocks from our home have just been cleared for a "planned community". I never thought I would be happy to witness the loss of that beautiful countryside because it meant that we wouldn't be subjected to their chemical spraying now. We loved the trees, but I remember several of our neighbors would keep their children indoors for a few days after the spraying, and we would lay low, too. I can't trace my sensitivity to Dursban and that orchard because, I was already very ill years before we moved here from Seattle. But I do remember that we had just moved into a brand new house around the time I became so sensitive. I suspected all the "new" chemicals in the finishes, carpets, and compounds used in construction. It seemed to happen overnight.
Roy Piwovar
Posted on Wednesday, December 13, 2000 - 4:11 pm:   Delete PostPrint Post   Ban Poster IP (Moderator/Admin only)

This article blames Monsanto and others as purveyors of poison:

http://www.usnews.com/usnews/issue/000619/poison.htm
MEMorrisNJ
Posted on Wednesday, December 13, 2000 - 6:48 pm:   Delete PostPrint Post   Ban Poster IP (Moderator/Admin only)

If anyone has any aspartame left, I read somewhere that it worked quite well for someone in killing carpenter ants! I think I saw this at
http://www.dorway.com -- not certain. Deb S: Thank you for sharing your experiences.
Deb S
Posted on Wednesday, December 13, 2000 - 8:19 pm:   Delete PostPrint Post   Ban Poster IP (Moderator/Admin only)

Deb A. - If your new home (or anyone else's) was built before 1988, there's a possibility it was treated with chlordane:

"Chlordane was the pesticide used to prevent or eliminate termites during the 1950's, 60's, 70's and 80's. However, after many reports of serious illness among both adults and children following its application and links to cancer in animals, chlordane was finally banned by the EPA in March of 1988. Unfortunately, the ban did not take place until over 30 million homes throughout the U.S. had been treated. Concerns in Florida are even greater because of the increased termite problem and the fact that research shows chlordane is higher in homes built on sandy soils.

"Most homeowners are unaware that just before the concrete slab was poured for their home's foundation, a pesticide company had come in and saturated the soil with 100 gallons of chlordane per 1000 square feet of area. People were literally building their homes on top of a toxic chemical dump. The public was reassured by the pesticide industry and entomologists that this was a safe procedure and that the chemical would not enter into the home because of the barrier provided by the cement foundation. However, this turned out not to be the case."

"Homes Remain Contaminated For Decades
"Chlordane is such a highly toxic and persistent chemical that homes treated 20-30 years ago are still showing unsafe levels of chlordane in the indoor air. The problem occurs because the hundreds of gallons of chlordane underneath the home are slowly evaporating, rising through cracks in the foundation or around plumbing pipes and entering the home."

http://www.chem-tox.com/chlordane/default.htm
Roy Piwovar
Posted on Thursday, December 14, 2000 - 12:43 am:   Delete PostPrint Post   Ban Poster IP (Moderator/Admin only)

This article lists 92 symptoms of aspartame poisoning:

http://www.health.microworld.com/html/aspartame_92.html
MEMorrisNJ
Posted on Tuesday, December 26, 2000 - 7:42 pm:   Delete PostPrint Post   Ban Poster IP (Moderator/Admin only)

To help debate the topic of aspartame with others, it is probably worth visiting the following site that seems to support its use: http://www.quackwatch.com/04ConsumerEducation/QA/aspartame.html

As if an FDA recommendation would reassure me that it was safe to use! No way! Also, the home page gives other "interesting" perspectives on a number of health topics. See: http:www.quackwatch.com
Roy Piwovar
Posted on Tuesday, January 09, 2001 - 7:03 pm:   Delete PostPrint Post   Ban Poster IP (Moderator/Admin only)

My personal experience with aspartame is that it is anything but tame.

Unlike MSG, which gives me a dose-related reaction, nutrasweet gives me no reaction at all until I've ingested a certain amount. Then, a little bit more makes my head swim. It's sort of like filling a glass with water, when one drop more makes it spill over.
M-Y
Posted on Sunday, March 04, 2001 - 1:46 pm:   Delete PostPrint Post   Ban Poster IP (Moderator/Admin only)

I just went to several search engines and typed in
auxigro and found out that this substance is being used all over the world. Very scary.
Roy Piwovar
Posted on Sunday, March 04, 2001 - 5:22 pm:   Delete PostPrint Post   Ban Poster IP (Moderator/Admin only)

Per the site below, our own lawns, trees and gardens could end up being saturated with Auxigro:

"AuxiGro contains 29.2% processed free glutamic acid (MSG). Simplot is already using AuxiGro on potato crops in Idaho. I have already received reports of MSG-type reactions from potatoes. In fact, I had a life threatening attack from a baked potato.

If AuxiGro is as effective as its manufacturer claims in improving yield and size of fruits and vegetables, it will be used widely. The manufacturer wants the product to be used on all vegetation, including lawns and all trees.

Jack"

http://www.cybernaute.com/earthconcert2000/Aspartame.htm
Deb S
Posted on Sunday, March 04, 2001 - 8:05 pm:   Delete PostPrint Post   Ban Poster IP (Moderator/Admin only)

About halfway down the page that Roy cites above, appears this:
________________________________________

From: Jon Baum

Please be advised that the "natural flavorings" in Celestial Seasonings Tea contains "free glutamic acid", the bad part of MSG. This was confirmed by the manufacturer. All products with "natural flavoring" are suspect as most manufacturers refuse to disclose what their natural flavorings are and categorize them as proprietary information. If it goes in our bodies, we have a right to know what is in it. A complete list of "hidden sources of MSG" is available at http://www.truthinlabeling.org

Jon Baum
Mission Possible Nations Capitol
Webmaster- http://aspartamekills.com
_______________________________________

Now I know for certain to stay away from "herbal" teas that contain "natural flavoring."
MEMorrisNJ
Posted on Monday, March 05, 2001 - 8:33 am:   Delete PostPrint Post   Ban Poster IP (Moderator/Admin only)

Deb S - Thanks! Deb A. warned us about their blended teas almost a year ago and told us to be sure to read the ingredients. I still feel betrayed by a company that I have patronized for years so I sent them a complaint letter via their Customer Care site that you can reach via http://www.celestialseasonings.com
Roy Piwovar
Posted on Tuesday, March 13, 2001 - 1:09 am:   Delete PostPrint Post   Ban Poster IP (Moderator/Admin only)

The site below includes a diagram showing how glutamate destroys brain cells:

http://www.mds.qmw.ac.uk/anae/ischaemi.htm
M-Y
Posted on Wednesday, March 21, 2001 - 12:52 pm:   Delete PostPrint Post   Ban Poster IP (Moderator/Admin only)

Here is another website that you might find interesting. I got it today.
http://www.msgfree.com/
Carol H
Posted on Sunday, March 25, 2001 - 10:18 am:   Delete PostPrint Post   Ban Poster IP (Moderator/Admin only)

I just ran across a link that made my blood run cold. This company is a pharmaceutical company that makes celebrex, which is anti-inflammatory medication,that someone on this board said seems to help them. It turns out, this company wholly owns Monsanto. http://www.pnu.com/About/Index.asp They are manufacturing the problems so they can be the heroes. Reminds me of the rogue firefighter who is a closet arsonist.
Carol H
Posted on Sunday, March 25, 2001 - 10:37 am:   Delete PostPrint Post   Ban Poster IP (Moderator/Admin only)

Yup, the very same company that makes one of only two drugs on the market to treat pituitary tumors also owns the company that makes Nutrasweet, which causes them..... My pills cost $30 per tablet, yes, that's PER TABLET and it is estimated that 25% of all adult Americans are now walking around with pituitary tumors. Chaching$$, chaching$$. Monsanto will never run out of money.
Deb S
Posted on Sunday, March 25, 2001 - 11:55 am:   Delete PostPrint Post   Ban Poster IP (Moderator/Admin only)

Whoa -- giant Monsanto is but a wholly-owned subsidiary of a huge pharmaceutical company?! Yikes!!! First I thought I was mis-reading it and it was the other way around, but it's true! I wonder if Bill Moyers will mention this connection on his PBS special airing tomorrow night? (Trade Secrets: A Moyers Report, 9pm Pacific time, PBS)

"In addition to prescription pharmaceuticals, Monsanto Company, a wholly owned subsidiary of Pharmacia, is a leading provider of agricultural solutions to growers worldwide. Pharmacia also has a strong position in associated businesses, including consumer healthcare, animal health, plasma products, bulk pharmaceuticals (global contract manufacturing) and diagnostics (US and worldwide).

"Our Monsanto subsidiary is committed to finding solutions to the growing global needs for food and health by sharing common forms of science and technology among agriculture, nutrition, and health. Monsanto makes and markets high-value agricultural products and food ingredients."

Genetically-modified foods topping the list, no doubt. They should be good for a whole new array of health woes -- "requiring" new and costly prescription treatments.

And just what do they mean by "a strong position in associated businesses, including consumer healthcare ..."? They are robbing our health from us, and then selling it back to us at a high premium. Making us junkies against our will.

Carol - how often do you have to take your pituitary pills? Just one per day is $90/month. Wonder what the average net profit is on all of these new patented drugs? If one in four adults has a pituitary tumor, how many of those are actually diagnosed? What are the symptoms?
Roy Piwovar
Posted on Sunday, March 25, 2001 - 1:59 pm:   Delete PostPrint Post   Ban Poster IP (Moderator/Admin only)

Deb S.,

Per the site below, Monsanto, which has just been acquired by Pharmacia (also listed on the site), is the second largest agrochemical corporation in the world:

"Over $2.4 billion per year in sales. Monsanto dealt with the Germans during World War II. It produces the neurotoxin Aspartame (Nutrasweet) after having purchased Searle Company, who faked the original tests on the product and submitted false data to the FDA. It also produces a line of neurotoxic herbicides and other lethal chemicals."

http://www.delsol.net/~trufax/general/pharmind.html
Carol H
Posted on Sunday, March 25, 2001 - 4:45 pm:   Delete PostPrint Post   Ban Poster IP (Moderator/Admin only)

Deb, although I take one a week, the usual dose is 2 per week. For an average dose, it would actually be $260 per month, or $3120 per year. There is also the increased risk of cervical cancer from these meds too. It's the same drug that Parkinson's patients need to take in much higher doses. I shudder to think what it costs Parkinson's patients.
Deb S
Posted on Sunday, March 25, 2001 - 5:25 pm:   Delete PostPrint Post   Ban Poster IP (Moderator/Admin only)

Oops, left off a zero, didn't I? You could feed a person (maybe two) for a month for $260. :(
Roy Piwovar
Posted on Monday, March 26, 2001 - 4:22 am:   Delete PostPrint Post   Ban Poster IP (Moderator/Admin only)

Carol,

Don't forget to get tested every year.

http://pslgroup.com/dg/d182.htm
Carol H
Posted on Saturday, March 31, 2001 - 6:14 am:   Delete PostPrint Post   Ban Poster IP (Moderator/Admin only)

Thanks, Roy. They just tested me.

Guess what guys? I think I found some more helpful info that proves we're not all crazy. I found this on the discussion board after the Trade Secrets expose. To summarize, researchers have discovered that the link between Alzheimer's disaease and asthma - both inflammatory disorders are greatly affected by Nerve Growth Factor. In other words, an overstimulated nervous system is what in effect causes overreaction of the immune system and the cells formed in the inflammatory response can release even more of this NGF that caused the trouble in the first place. Got that? MSG is the gift that keeps giving. Well, here's the post:

Subject: The latest Asthma theory consistant with
Reply Posted by: neurological injuries
Date Posted: Fri Mar 30 1:51:27 US/Eastern 2001
Message:
Johns Hopkins Medical Institutions 20-May-00 New Theory for Allergic Diseases Library: MED Keywords: ALLERGY NERVE GROWTH FACTOR NGD ASTHMA Description: Johns Hopkins researchers have discovered that a nervous system protein may have a significant role in asthma, hay fever and other allergies. According to the May American Journal of Respiratory and Critical Care Medicine, the protein, nerve growth factor, may be responsible for making allergy sufferers more sensitive to irritants such as tobacco smoke. May 18, 2000 Johns Hopkins Medical Institutions' news releases are available on an EMBARGOED basis on Newswise at http://www.newswise.com and from the Office of Communications and Public Affairs' direct e-mail news release service. To enroll, call 410-955-4288 or send e-mail to bsimpkins@jhmi.edu. On a POST-EMBARGOED basis find them at http://hopkins.med.jhu.edu. RESEARCHERS PRESENT NEW THEORY FOR ALLERGIC DISEASES Johns Hopkins researchers have discovered, to their surprise, that a nervous system protein may have a significant role in asthma, hay fever and other allergies. According to the new research reported in the May issue of the American Journal of Respiratory and Critical Care Medicine, the protein, nerve growth factor (NGF), may be responsible for making allergy sufferers more sensitive to irritants such as tobacco smoke. "Hay fever and asthma now seem to derive from events not only in the respiratory system, but also from a nervous system that is overreacting to stimuli," says Vassilis Koliatsos, M.D., an associate professor of pathology, neurology and neuroscience at the Johns Hopkins School of Medicine. In the United States, hay fever, medically known as allergic rhinitis, affects up to 36 million people and asthma affects about 14 million, at a cost of several billions of dollars per year. For decades, scientists have known that individuals who have allergies and asthma are more reactive to irritants such as cold, dry air and tobacco smoke, but until now, they haven't known why. Hopkins allergy researchers took to the trail of NGF for several reasons. First, Koliatsos, who is an expert on the use of NGF in experiments to treat nerve and brain disorders, informed the allergy researchers that using NGF to treat Alzheimer's caused patients excessive pain. NGF, found naturally in the body, is a small, potent molecule that helps maintain certain nerve cells and prods other nerve cells to grow and communicate with others. "It looked like the pain syndromes we saw in these patients shared many of the same mechanisms with respiratory allergy," says Koliatsos. Specifically, both involved an inflammatory response by cells in lung or nerves. Secondly, Hopkins allergy researchers had found that individuals who were hyper-responsive to irritants had nerves in their airways that were abnormally reactive. And thirdly, researchers at Hopkins and other institutions had shown that, in animal studies, NGF could cause significant changes in nerve fibers. For example, mice that were genetically engineered to produce excessive amounts of NGF in their lungs developed increased density of nerves in the airways as well as increased responsiveness to irritants. To test whether an allergic reaction in humans would increase NGF, Alvin Sanico, M.D., an assistant professor of medicine at Hopkins, and his colleagues enlisted 20 volunteers who had hay fever and 10 who were healthy. As part of the study, the scientists collected nasal washings before and after administering ragweed or grass pollen extracts by nasal spray. They found that baseline levels of NGF in the nasal washings of the allergic group were significantly higher compared to the healthy group. In addition, they discovered that exposure to the allergen caused a significant increase in NGF levels in the allergic group but had no effect on the healthy individuals. "This finding provides further understanding of a very common disease and hopefully may open new possibilities for novel forms of treatment in the future," says Sanico, lead author of the study. For example, researchers in the future may identify a drug that could block the effects of these molecules and decrease hyper-responsiveness. "Our frustrations with the side effects of NGF in clinical trials for Alzheimer's disease and nerve disorders helped lead to this study," says Koliatsos. "It is very rewarding to see another clinical opportunity for this very interesting molecule." Sanico says the new discovery can bridge the two major features of allergic airway disease: inflammation (which causes typical allergy symptoms such as congestion) and hyper-responsiveness to irritants. During inflammation, cells that participate in an allergic reaction, such as mast cells and eosinophils, are stimulated, and these cells have now been shown to be capable of producing NGF. Sanico says more studies that are needed to further understand this new facet of allergic airway disease in humans are currently under way. The study was funded by grants from the National Institutes of Health and Johns Hopkins. The authors of the study are Alvin Sanico, Todd Gleeson, Susan Bora, David Proud, Vassilis Koliatsos and Alkis Togias from Johns Hopkins in Baltimore, Maryland, as well as John Bienenstock and Andrzej Stanisz from McMaster University in Ontario, Canada. --JHMI-- Media Contact: Kate O'Rourke (410)955-8665 korourke@jhmi.edu http://www.newswise.com/articles/2000/5/ALLERGY5.JHM.html
Roy Piwovar
Posted on Monday, April 16, 2001 - 7:01 pm:   Delete PostPrint Post   Ban Poster IP (Moderator/Admin only)

Some NoMSG archives that their site had lost were sent to me by MEMorrisNJ, including a links archive. I have reposted them in their discussion board. They are no longer categorized, but the links in the various postings still work:

http://www.NoMSG.com
Judy T
Posted on Friday, April 20, 2001 - 8:05 am:   Delete PostPrint Post   Ban Poster IP (Moderator/Admin only)

Roy, What a kind service you have provided, and also to MEMorrisNJ who saved some of the archives. I just looked at some of the past discussions and was able to find one I had been wanting to reread, that is Carol H's first postings on taurine. I need a whole day off from other activities (or maybe more) and reread and remake notes on all postings. There is so much to know, so much to consider, and so much available in all our postings that I want to revisit everything. Thank you Roy and MEMorris for taking the time, the energy and the consideration for working with those archival records.
MEMorrisNJ
Posted on Friday, April 20, 2001 - 2:46 pm:   Delete PostPrint Post   Ban Poster IP (Moderator/Admin only)

Thanks for doing that Roy. Those earlier postings certainly helped me survive last year and I am glad to see you were able to resurrect them from my "mess". They contain valuable feedback from many NoMSGers that others may use and may be worth reviewing again.
Carol H
Posted on Friday, April 20, 2001 - 3:51 pm:   Delete PostPrint Post   Ban Poster IP (Moderator/Admin only)

Thank you so much, Roy and MEMorris. There were a lot of discussions with Tom Fernstrom about the liver and MSGs effects on it that I feel were extremely valuable. I was so happy to see that was all saved:)
Deb A.
Posted on Friday, April 20, 2001 - 5:23 pm:   Delete PostPrint Post   Ban Poster IP (Moderator/Admin only)

What a team! Many thanks! Mike keeps backing up the bulletin board postings on a regular basis. Thought you would want to know.
Carol H
Posted on Saturday, April 21, 2001 - 8:11 am:   Delete PostPrint Post   Ban Poster IP (Moderator/Admin only)

I started updating my website again, so there will be new pages from here on in. http://www.basicfare.com. I just put a new recommended reading section on it today. I'll be really working on it in earnest now that I have more time. Let me know what you think.
Deb A.
Posted on Saturday, April 21, 2001 - 6:35 pm:   Delete PostPrint Post   Ban Poster IP (Moderator/Admin only)

Carol, You've been very busy! I read all the pages and they are excellent, needless to say....very professionally written. The MSG page is great, and I'm looking forward to the ones on sulfites and caffeine. This is so great. Up to just a short time ago, people searching for info on excitotoxins had so little available to them. Now they will get an "earful". This will have far reaching effects.
Judy T
Posted on Sunday, April 22, 2001 - 12:03 pm:   Delete PostPrint Post   Ban Poster IP (Moderator/Admin only)

Carol: I'm looking forward to the Taurine section. Wonderful to have much information capsulized.
Judy T
Posted on Thursday, July 12, 2001 - 4:48 pm:   Delete PostPrint Post   Ban Poster IP (Moderator/Admin only)

I didn't know where to post this. Interesting books on www@prestigepublishing.com . The books may be almost over the edge but I like people like this; I learn more from them then some moderates. I'm ordering some of the books to see what connections there might be.

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